Compound C108

CAS No. 15533-09-2

Compound C108( —— )

Catalog No. M35036 CAS No. 15533-09-2

Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and esophageal squamous cell carcinoma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 58 In Stock
5MG 78 In Stock
10MG 125 In Stock
25MG 244 In Stock
50MG 389 In Stock
100MG 565 In Stock
500MG 1215 In Stock
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Biological Information

  • Product Name
    Compound C108
  • Note
    Research use only, not for human use.
  • Brief Description
    Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and esophageal squamous cell carcinoma.
  • Description
    Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis.
  • In Vitro
    Western Blot Analysis Cell Line:G3BP2-overexpressing KYSE410 cells, LINC01554-transfected KYSE30 cells Concentration:4 μM Incubation Time:24 h Result:Decreased the protein level of G3BP2 and HDGF.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GTPase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    15533-09-2
  • Formula Weight
    270.28
  • Molecular Formula
    C15H14N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (92.50 mM; Ultrasonic )
  • SMILES
    C\C(=N/NC(=O)c1ccccc1O)c1ccccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gupta N, et al. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1033-1038.?
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